Jinda Fan
Contact
fanjinda@msu.edu
Office: 517-432-2097
Lab: 517-353-3686
IQ DIVISION – Chemical Biology
Departmental AFFILIATIONS
About
Jinda Fan, Ph.D. is an Assistant Professor of Pharmacology & Toxicology, Chemistry and Radiology at Michigan State University. His research lies at the interface of radiochemistry, molecular imaging, and targeted therapy, with a focus on imaging molecular targets that drive key biological processes in cancer and other diseases. His lab aims to develop innovative radiopharmaceuticals for both diagnostic and therapeutic applications, advancing precision medicine.
Dr. Fan received his B.S. and M.S. degrees in Chemistry from the East China University of Science and Technology, followed by a Ph.D. in Chemistry from Southern Illinois University Carbondale. He completed postdoctoral training in the Department of Radiology at Washington University in St. Louis, one of the leading centers in molecular imaging and radiopharmaceutical science. Prior to joining MSU, Dr. Fan served on the faculty in the Department of Radiology at the University of Alabama at Birmingham.
His work has been supported by NIH and ACS, and he is actively involved in interdisciplinary collaborations.
About Fan Lab
Fan Lab at Michigan State University is dedicated to advancing the frontiers of molecular imaging and targeted radiotherapy. Our interdisciplinary research lies at the intersection of Imaging, Therapy, and Radiochemistry, as reflected in our logo.
We specialize in the development of novel radiopharmaceuticals and molecular probes for diagnostic imaging and therapeutic applications, particularly in oncology. Our research efforts include:
- Imaging: Developing radiolabeled probes for PET/SPECT imaging to visualize disease biology at the molecular level.
- Therapy: Designing targeted radionuclide therapies using alpha and beta emitters to selectively eradicate cancer cells while sparing healthy tissues.
- Radiochemistry: Synthesizing and optimizing radiotracers, including chelators and isotope labeling strategies, to enable precise and reproducible radiopharmaceutical production.
Fan Lab integrates cutting-edge chemistry, biology, and imaging science to translate basic discoveries into clinical innovations. We collaborate across disciplines to improve early disease detection, personalize therapy, and enhance patient outcomes.
aimed at translating radiopharmaceutical science into clinical impact.
Selected Publications:
- Protective Group-Dependent Iridium-Catalyzed CH Borylations of Levodopa. The Journal of Organic Chemistry (2025)
- 212Bi-Macroaggregated Albumin Inhibited Mouse Melanoma Growth by Regulating Cell Cycle Checkpoint Markers Without Promoting Living Cell Repopulation. Journal of Nuclear Medicine (2025)
- Species-Specific Hepatic Uptake of [64Cu]Cu-EOB-NOTA, A Newly Designed Hepatospecific PET Agent. Molecular Imaging and Biology (2025)
- The Development and Challenges of PET/MRI Dual-Modality Imaging Probes—An Update. Journal of Magnetic Resonance Imaging (2025)
- Brown Adipose Tissue as a Unique Niche for Islet Organoid Transplantation: Insights From In Vivo Imaging. Transplantation Direct (2024)
- Design and Construction of a Radiochemistry Laboratory and cGMP-Compliant Radiopharmacy Facility. Pharmaceuticals (2024)
- Distribution of insulin in primate brain following nose-to-brain transport. Alzheimer’s and Dementia: Translational Research and Clinical Interventions (2024)
- On the inconsistencies in previously reported protections of the catechol moiety of L-DOPA. Tetrahedron Letters (2024)
- Intra-Arterial Delivery of Radiopharmaceuticals in Oncology: Current Trends and the Future of Alpha-Particle Therapeutics. Pharmaceutics (2023)
- Deep learning-enabled quantification of simultaneous PET/MRI for cell transplantation monitoring. iScience (2023)
- Omniparticle Contrast Agent for Multimodal Imaging: Synthesis and Characterization in an Animal Model. Molecular Imaging and Biology (2023)
- Pb-214/Bi-214-TCMC-Trastuzumab inhibited growth of ovarian cancer in preclinical mouse models. Frontiers in Chemistry (2023)