Research Associate (#630006) – Bachmann Lab
The Institute for Quantitative Health Science and Engineering (IQ) and the Department of Microbiology and Molecular Genetics (MMG) at Michigan State University invite applications from outstanding candidates for the position of Research Associate (postdoctoral researcher) in the laboratory of Dr. Michael H. Bachmann.
The Bachmann Lab at IQ focuses on two biomedical issues of high public health significance: cancer immunology and antimicrobial resistance. In the later project, the subject of this job announcement, we are investigating plant-derived compounds as alternative antibiotics. According to the latest CDC report, ~35,000 Americans die from infections with antibiotic resistant bacteria. We are therefore investigating complex plant compounds for their activity against gastrointestinal pathogens classified by the CDC as the biggest threats. For in vitro screening and in vivo analysis, we are using bioluminescently labeled bacterial pathogens, such as E. coli, Salmonella, and Vibrio cholerae, and bioluminescence imaging to assess bacterial survival and thus antibacterial efficacy. Our preliminary data show strong antibacterial activity of several plant compounds and extracts.
The primary goal of the successful candidate will be to further characterize these compounds, determine the signaling and metabolic pathways they affect through RNAseq and mutant analysis, assess cytotoxicity to mammalian cells, and test the compounds in mouse models of infection. Job duties will also include, but are not limited to, mentoring undergraduate and graduate students in the lab; collaborate in related secondary projects and collaborations with other IQ and MMG labs; and write papers and give presentation about the research conducted. The successful candidate will have knowledge of bacteriology, molecular biology and genetics, human and mouse cell culture assays, and experimental animal studies. Knowledge of GC-MS-based mass spectrometry, transcriptomics, and large data analysis (R, Python, HPCC) will be given special consideration
To apply for this position, please visit the MSU careers site.
Research Associate (#718685) – Li Lab
The Institute for Quantitative Health Science and Engineering and the Department of Biomedical Engineering at Michigan State University is seeking two Postdoctoral Research Associates in the Jinxing Li Lab (http://www.lab-li.com/). The Li Lab focuses on creating miniaturized biosensors and medical robots for disease diagnostics and treatment. Our lab is based in the brand-new IQ/Bioengineering Building. The successful candidate will have the opportunity to develop cutting-edge biomedical technologies, learn new skills, and be part of an enjoyable workplace. Candidates from diverse cultural and educational backgrounds are especially encouraged to apply.
Specifically, the successful applicant will be expected to:
- Build engineering solutions to solve the problems in biology and medicine
- Collaborate with researchers across different disciplines and institutions
- Mentor undergraduate and graduate students in the lab
- Present findings and data in lab meetings, publications, and presentations
- Purchase, setting up, and maintaining equipment necessary to conduct research.
This position is a 12-month fixed-term appointment. Renewal of position is based on funding and performance.
To apply for this position, please visit the MSU Careers site.