Dana Spence

Portrait photo of Dana SpenceContact

517-353-1116
spenceda@msu.edu
View publications on MSU Scholars
Biomedical Devices Division

About

Dana Spence is a professor of biomedical engineering and chemistry. He leads a research group whose interests lie at the interface of analytical chemistry, bioengineering, pharmacology, and hematology.

Dr. Spence earned his B.S. in chemistry from Grand Valley State University and his Ph.D. in chemistry at Michigan State University. He previously held faculty appointments in chemistry at Saint Louis University and Wayne State University.

The Spence Group

The Spence Group applies analytical tools to solve problems in diabetes, sickle cell anemia, transfusion medicine, and platelet physiology. They also develop new technologies using 3D printing to facilitate our studies and help answer important biomedical questions.

One major focus is investigating and defining new roles for red blood cells in such autoimmune diseases as Type 1 diabetes and multiple sclerosis. Key to the studies is C-peptide, the 31–amino acid peptide that is co-secreted with insulin from the pancreatic β-cells. When formulated correctly, preliminary evidence suggests that this peptide may be the missing link in complications associated with both diseases listed above.

A 3D printed device helps monitor cell to cell communication between pancreatic secretions and the circulation on a controlled in vitro platform